Thiamin deficiency and uncomplicated falciparum malaria in Laos

Clinically Unapparent Infantile Thiamin Deficiency in Vientiane, Laos

BACKGROUND Beriberi occurs in Vientiane, Lao PDR, among breastfed infants. Clinical disease may be the tip of an iceberg with subclinical thiamin deficiency contributing to other illnesses. Thiamin treatment could improve outcome. METHODOLOGY/PRINCIPAL FINDINGS A cohort of 778 sick infants admitted during one year without clinical evidence of beriberi were studied prospectively and erythrocyt...

Pituitary-adrenal function in uncomplicated falciparum malaria.

To investigate pituitary-adrenal function in acute uncomplicated falciparum malaria, we performed an overnight dexamethasone suppression test in 13 Vietnamese adults with acute malaria and 6 healthy controls. After blood samples were taken for serum cortisol and plasma ACTH at 23.00 hours on the admission day, 1 mg dexamethasone was given and further samples were taken at 08.00, 16.00 and 23.00...

Treatment of Uncomplicated Plasmodium falciparum Malaria

Background: This paper reports for the first time, the antimalarial efficacy of a five-day course of paediatric formulation of “vocamine” named MMH8 from Millenia Hope Inc for the treatment of uncomplicated Plasmodium falciparum malaria. Methods: We used the standard 14-day WHO protocol to assess therapeutic responses in children less than 5 years in Bangui (Central African Republic) between Ja...

Changes in platelet count in uncomplicated and severe falciparum malaria.

This study investigated alterations in platelet counts pre- and post-treatment with artemisinin derivatives in uncomplicated and severe falciparum malaria. Serial platelet counts were taken over 4 weeks for 110 uncomplicated and 110 severe falciparum malaria patients admitted to the Hospital for Tropical Diseases during 2005-2008. On admission, prior to treatment, thrombocytopenia was found in ...

quinine in pregnant women with uncomplicated falciparum malaria in Uganda